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Dynamic modelling and simulation of a post-combustion CO capture process for coal-fired power plants
《化学科学与工程前沿(英文)》 2022年 第16卷 第2期 页码 198-209 doi: 10.1007/s11705-021-2057-7
关键词: CO2 capture post-combustion capture simulation dominant factor
null
《医学前沿(英文)》 2016年 第10卷 第3期 页码 311-319 doi: 10.1007/s11684-016-0460-0
We evaluated the roles of calpain cleavage-related mutations of the integrin β3 cytoplasmic tail in integrin αIIbβ3 bidirectional signaling using a trans-dominant inhibition model. Chimeric Tac-β3 proteins (i.e., Tac-β3, Tac-β3D741, Tac-β3D747, Tac-β3D754, Tac-β3D759, and Tac-β3DNITY) consisting of the extracellular and transmembrane domains of human IL-2 receptor (Tac) and the human integrin β3 cytoplasmic domain were stably expressed in the 123 CHO cells harboring human glycoprotein Ib-IX and wild-type integrin αIIbβ3. The different cells were assayed for stable adhesion and spreading on immobilized fibrinogen, and for binding soluble fibrinogen representing outside-in and inside-out signaling events, respectively. The chimeric protein Tac-β3 inhibited, and Tac-β3DNITY partially attenuated stable adhesion and spreading. Tac-β3, Tac-β3D759, Tac-β3DNITY, and Tac-β3D754, but not Tac-β3D747 or Tac-β3D741, impaired the soluble fibrinogen binding. Results indicated that the bidirectional signaling was significantly inhibited by Tac-β3 and Tac-β3DNITY, albeit to a much lesser extent. Moreover, only inside-out signaling was impaired in the 123/Tac-β3D759 and 123/Tac-β3D754 cells in contrast to an intact bidirectional signaling in the 123/Tac-β3D747 and 123/Tac-β3D741 cells. In conclusion, the calpain cleavage of integrin β3 resulted in the regulatory effects on signaling by interrupting its interaction with cytoplasmic proteins rather than altering its conformation, and may thus regulate platelet function.
关键词: integrin β3 signal transduction trans-dominant inhibition model
Jiuxiao Hao, Xiujin Wang, Hui Wang
《环境科学与工程前沿(英文)》 2017年 第11卷 第1期 doi: 10.1007/s11783-017-0896-8
关键词: Polyhydroxyalkanoates (PHAs) Valerate Mixed culture 3-hydroxyvalerate (3HV) Propionate
YANG Shengxiang,LIANG Shichu,YI Langbo,XU Bibo,CAO Jianbing,GUO Yifeng,ZHOU Yu
《环境科学与工程前沿(英文)》 2014年 第8卷 第3期 页码 394-404 doi: 10.1007/s11783-013-0602-4
关键词: Mn mine tailings heavy metal accumulation phytostabilization
Hydrogen production by catalytic gasification of cellulose in supercritical water
GUAN Yu, PEI Aixia, GUO Liejin
《化学科学与工程前沿(英文)》 2008年 第2卷 第2期 页码 176-180 doi: 10.1007/s11705-008-0026-z
关键词: reaction temperature combination catalytic effect dominant product
Simulation of cross-flow-induced vibration of tube bundle by surface vorticity method
WANG Fenghao, JIANG Gedong, Lin John Zhang
《能源前沿(英文)》 2008年 第2卷 第3期 页码 243-248 doi: 10.1007/s11708-008-0049-7
关键词: dominant sub-critical Reynolds staggered Vorticity three-row
Role of the forkhead transcription factor FOXO-FOXM1 axis in cancer and drug resistance
null
《医学前沿(英文)》 2012年 第6卷 第4期 页码 376-380 doi: 10.1007/s11684-012-0228-0
The forkhead transcription factors FOXO and FOXM1 have pivotal roles in tumorigenesis and in mediating chemotherapy sensitivity and resistance. Recent research shows that the forkhead transcription factor FOXM1 is a direct transcriptional target repressed by the forkhead protein FOXO3a, a vital downstream effector of the PI3K-AKT-FOXO signaling pathway. Intriguingly, FOXM1 and FOXO3a also compete for binding to the same gene targets, which have a role in chemotherapeutic drug action and sensitivity. An understanding of the role and regulation of the FOXO-FOXM1 axis will impact directly on our knowledge of chemotherapeutic drug action and resistance in patients, and provide new insights into the design of novel therapeutic strategy and reliable biomarkers for prediction of drug sensitivity.
关键词: FOXO3a FOXM1 transcription factor cancer drug resistance tumorigenesis
Chunji YAN, Maozhao XIE,
《能源前沿(英文)》 2010年 第4卷 第2期 页码 198-204 doi: 10.1007/s11708-009-0054-5
关键词: liquid jet dominant wave number compressibility instability
Numerical simulation of laminar premixed combustion in a porous burner
ZHAO Pinghui, CHEN Yiliang, LIU Minghou, DING Min, ZHANG Genxuan
《能源前沿(英文)》 2007年 第1卷 第2期 页码 233-238 doi: 10.1007/s11708-007-0032-8
关键词: interphase mixture dominant Premixed combustion premixed combustion
LSSVM-based approach for refining soil failure criteria and calculating safety factor of slopes
Shiguo XIAO; Shaohong LI
《结构与土木工程前沿(英文)》 2022年 第16卷 第7期 页码 871-881 doi: 10.1007/s11709-022-0863-8
关键词: slope stability safety factor failure criterion least square support vector machine
lncR-GAS5 upregulates the splicing factor to impair endothelial autophagy, leading to atherogenesis
《医学前沿(英文)》 2023年 第17卷 第2期 页码 317-329 doi: 10.1007/s11684-022-0931-4
关键词: lncR-GAS5 miR-193-5p splicing factor SRSF10 autophagy atherogenesis
The calculation of equivalence factor for ecological footprints in China: a methodological note
Moucheng LIU,Wenhua LI,Dan ZAHNG,Ning SU
《环境科学与工程前沿(英文)》 2015年 第9卷 第6期 页码 1015-1024 doi: 10.1007/s11783-014-0670-0
关键词: ecological footprint equivalence factor net primary production biological capacity land types
《结构与土木工程前沿(英文)》 2021年 第15卷 第4期 页码 877-894 doi: 10.1007/s11709-021-0756-2
关键词: bridges multi-lane factor traffic load lane load disparity multi-truck presence weigh-in-motion data
Zheng WANG, Zai-Sha MAO, Chao YANG, Qinghua ZHANG, Jingcai CHENG
《化学科学与工程前沿(英文)》 2009年 第3卷 第3期 页码 272-281 doi: 10.1007/s11705-009-0023-x
关键词: stirred tank numerical simulation precipitation shape factor crystal kinetics
The formation mechanism and the influence factor of residual stress in machining
null
《机械工程前沿(英文)》 2014年 第9卷 第3期 页码 265-269 doi: 10.1007/s11465-014-0311-0
Residual stresses generated in cutting process have important influences on workpiece performance. The paper presents a method of theoretical analysis in order to explicate the formation mechanism of residual stresses in cutting. An important conclusion is drawn that the accumulated plastic strain is the main factor which determines the nature and the magnitude of surface residual stresses in the workpiece. On the basis of the analytical model for residual stress, a series of simulations for residual stress prediction during cutting AISI 1045 steel are implemented in order to obtain the influences of cutting speed, depth of cut and tool edge radius on surface residual stress in the workpiece. And these influences are explained from the perspective of formation mechanism of residual stress in cutting. The conclusions have good applicability and can be used to guide the parameters selection in actual production.
关键词: residual stress analytical model strain plastic cutting parameter
标题 作者 时间 类型 操作
Dynamic modelling and simulation of a post-combustion CO capture process for coal-fired power plants
期刊论文
Roles of integrin β3 cytoplasmic tail in bidirectional signal transduction in a trans-dominant inhibition
null
期刊论文
Investigation of polyhydroxyalkanoates (PHAs) biosynthesis from mixed culture enriched by valerate-dominant
Jiuxiao Hao, Xiujin Wang, Hui Wang
期刊论文
Heavy metal accumulation and phytostabilization potential of dominant plant species growing on manganese
YANG Shengxiang,LIANG Shichu,YI Langbo,XU Bibo,CAO Jianbing,GUO Yifeng,ZHOU Yu
期刊论文
Hydrogen production by catalytic gasification of cellulose in supercritical water
GUAN Yu, PEI Aixia, GUO Liejin
期刊论文
Simulation of cross-flow-induced vibration of tube bundle by surface vorticity method
WANG Fenghao, JIANG Gedong, Lin John Zhang
期刊论文
Stability of an annular viscous liquid jet in compressible gases with different properties inside and outside of the jet
Chunji YAN, Maozhao XIE,
期刊论文
Numerical simulation of laminar premixed combustion in a porous burner
ZHAO Pinghui, CHEN Yiliang, LIU Minghou, DING Min, ZHANG Genxuan
期刊论文
LSSVM-based approach for refining soil failure criteria and calculating safety factor of slopes
Shiguo XIAO; Shaohong LI
期刊论文
lncR-GAS5 upregulates the splicing factor to impair endothelial autophagy, leading to atherogenesis
期刊论文
The calculation of equivalence factor for ecological footprints in China: a methodological note
Moucheng LIU,Wenhua LI,Dan ZAHNG,Ning SU
期刊论文
A practical multi-lane factor model of bridges based on multi-truck presence considering lane load disparities
期刊论文
Numerical investigation of the influence of kinetics and shape factor on barium sulfate precipitation
Zheng WANG, Zai-Sha MAO, Chao YANG, Qinghua ZHANG, Jingcai CHENG
期刊论文